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KMID : 0381919990290020201
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Korean Journal of Microscopy
1999 Volume.29 No. 2 p.201 ~ p.209
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Remodeling of the Epidermis during Skin Wound Healing in Bombina orientalis
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Jeong Moon-Jin
Moon Myung-Jin
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Abstract
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Remodeling of epithelial cells during wound healing in the skin of the Korean fire-bellied toad, Bombina orientalis, were examined using the scanning and transmission electron microscopical analyses. Artificial wounds were induced on the dorsal surface of the skin by excision, and reared in special cages with normal diets for up to 31 days after injury. From 4 days after wounding, regenerated epithelial cells are more rapidly migrated to wounding area, and remodeling of tissue components are proceeded gradually. Especially, formation of basal lamina between regenerated epithelium and dermis, and reconstruction of cellular junctions such as desmosomes (among the regenerated epithelial cells) and hemidesmosomes (between basal epithelial cells and basal lamina) are detected through fine structural analysis from 10 days after injury. Parakeratosis of regenerated epithelial cells observed during 16 to 19 days after wounding.
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KEYWORD
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Remodeling, Epidermis, Skin, Wound healing, Bombina orientalis
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